Welcome on MINT homepage

The MINT laboratory is funded by the University of Angers, as well as the French National Institute of Health and Medical Research (INSERM) and The French National Center for Scientific Research (CNRS). Located within the Hospital Facility, the MINT laboratory consists of 40 researchers and PhD students with expertise in diverse fields including; colloids and interfaces physical-chemistry; galenic; chemical engineering for pharmaceutical formulation; biological research; and imaging. All our research is focused on the design of nano- and micro-scaled vectors for the delivery of therapeutics (encompassing proteins, anti-cancer drugs, DNA, SiRNA, etc.) and/or imaging probes.

News

3 students from European partner Universities are joining MINT

We are delighted to welcome 3 students from European partner Universities

Soutenance de Thèse de Mr Norraseth Kaeokhamloed

Evaluation of lipid nanocapsules (LNCs) for oral absorption using new quantitative FRET technique

Welcome to the EMJMD Nanomed and Nanopharma master students.

We are proud to Welcome the2022-2023 EMJMD Nanomed and Nanopharma master students.

Academic training

Master 2 NanoPharma Nanomedicines and Pharmaceutical R&D

European Mundus Joint master Degree " Nanomedicine for drug delivery"

Recently published

		Biological activity of gold nanoparticles combined with the NFL-TBS.40-63 peptide, or with other cell penetrating peptides, on rat glioblastoma cells. Griveau A, Arib C, Spadavecchia J, Eyer J. link to publisher link to intranet
		Ferrocifen stealth LNCs and conventional chemotherapy: A promising combination against multidrug-resistant ovarian adenocarcinoma Idlas P, Ladaycia A, Némati F, Lepeltier E, Pigeon P, Jaouen G, Decaudin D & Passirani C link to publisher link to intranet
		Cell penetrating peptide (CPP) gold(iii) – complex – bioconjugates: from chemical design to interaction with cancer cells for nanomedicine applications Arib C, Griveau A, Eyer J & Spadavecchia J link to publisher link to intranet full text
		Reactive precipitation of vaterite calcium carbonate microspheres insupercritical carbon dioxide-water dispersion by microfluidics Legout P, Lefebvre G, Bonnin M, Gimel JC, Benyahia L, Gibaud A, Marre S, Simonsson C, Wang S, Colombani O & Calvignac B link to publisher link to intranet
		FRET as the tool for in vivo nanomedicine tracking Kaeokhamloed N, Legeay s & Roger E link to publisher link to intranet
		Lipid nanocapsules for intracellular delivery of microRNA: A first step towards intervertebral disc degeneration therapy Le Moal B, Lepeltier E, rouleau D, Le Visage C, Benoit JP, Passirani C, Guicheux J, Fusellier M & Clouet J link to publisher link to intranet
		Can magnetization transfer magnetic resonance imaging help for the follow-up of synthetic hernia composite meshes fate? A pilot study Franconi F, Lefranc O, Radlovic A & Lemaire L link to publisher link to intranet
		Tailoring PEGylated nanoparticle surface modulates inflammatory response in vascular endothelial cells Therani SF, Rabanel J-M, Legeay S, Cayon J, Riou J, Saulnier P, Marleau S, Roullin VG, Hildgen P & Bastiat G link to publisher link to intranet
		DDS for oral administration of antimicrobial peptides: Promising tools to treat infectious diseases Deshayes C, Arafath MD, Apaire-Marchais V & Roger E link to publisher link to intranet open acess
		Cell penetrating peptide decorated magnetic porous silicon nanorods for glioblastoma therapy and imaging Chaix A, Griveau A, Defforge T, Grimal V, Le Borgne B, Gautier G and Eyer J link to publisher link to intranet
		Impact of anti-PDGRFa antibody surface functionnalization on LNC uptake by oligodendrocyte progenitor cells Labrak Y, Heurtault B, Frisch B, Saulnier P, Lepeltier E, Miron VE, Muccioli GG & Des Rieux A link to publisher link to intranet
		Green Nanotechnology - An innovative pathway towards biocompatible and medically relevant gold nanoparticles Thipe VG, Karikachery AR, Cakilkaya P, Farooq U,Genedy HH, Kaeokhamloed N, Phan DH, Rezwan R, Tezcan G, Roger E, Katti KV. link to publisher link to intranet
		Interfacial tension of ethanol, water, and their mixtures in high pressure carbon dioxide: Measurements and modeling Fabien A, Lefebvre G, Calvignac B, Legout P, Badens E &Crampon C link to publisher link to intranet
		Epoxiconazole profoundly alters rat brain and properties of neural stem cells Hamdi H, Graiet I, Abid-Essefi S & Eyer J link to publisher link to intranet
		Modulating undruggable targets to overcome cancer therapy resistance Passirani C, Vessières A, La Regina G, Link W & Silvestri R link to publisher link to intranet
		Stability of a high-concentrated aqueous solution of idarubicin stored in a polypropylene syringe for transarterial chemoembolization Bourcier B, Lagarce F & Lebreton V link to publisher link to intranet
		Azacitidine Omega-3 Self-Assemblies: Synthesis, Characterization, and Potent Applications for Myelodysplastic Syndromes. Baroud M, Lepeltier E, El-Makhour Y, Lautram N, Bejaud J, Thepot S & Duval O link to publisher link to intranet
		The evolution of nucleosidic analogues: self-assembly of prodrugs into nanoparticles for cancer drug delivery Baroud M., Lepeltier E., Thepot S., El-Makhoure Y. & Duval O. link to publisher link to intranet
		Organic nanoparticle tracking during pharmacokinetic studies Bonnet S., Elfatairi R., Franconi F., Roger E. & Legeay S. link to publisher link to intranet
		Local delivery and glioblastoma: Why not combining sustained release and targeting? *Gazaille C., Sicot M., Saulnier P., Eyer J & Bastiat G* link to publisher link to intranet
		Microbiota and nanoparticles: Description and interactions Ladaycia A, Passirani C & Lepeltier E link to publisher link to intranet

Granting agencies