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Micro et Nanomédecines translationnelles

Welcome on MINT homepage

The MINT laboratory is funded by the University of Angers, as well as the French National Institute of Health and Medical Research (INSERM) and The French National Center for Scientific Research (CNRS). Located within the Hospital Facility, the MINT laboratory consists of 40 researchers and PhD students with expertise in diverse fields including; colloids and interfaces physical-chemistry; galenic; chemical engineering for pharmaceutical formulation; biological research; and imaging. All our research is focused on the design of nano- and micro-scaled vectors for the delivery of therapeutics (encompassing proteins, anti-cancer drugs, DNA, SiRNA, etc.) and/or imaging probes.

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News

Academic training

 

Master 2 NanoPharma Nanomedicines and Pharmaceutical R&D

 

European Mundus Joint master Degree " Nanomedicine for drug delivery"

Recently published

 

 

Reactive precipitation of vaterite calcium carbonate microspheres insupercritical carbon dioxide-water dispersion by microfluidics

Legout P, Lefebvre G, Bonnin M, Gimel JC, Benyahia L, Gibaud A, Marre S, Simonsson C, Wang S, Colombani O  & Calvignac B

link to publisher        link to intranet

 

FRET as the tool for in vivo nanomedicine tracking

Kaeokhamloed N, Legeay s & Roger E

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Lipid nanocapsules for intracellular delivery of microRNA: A first step towards intervertebral disc degeneration therapy

Le Moal B, Lepeltier E, rouleau D, Le Visage C, Benoit JP, Passirani C, Guicheux J, Fusellier M & Clouet J

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Can magnetization transfer magnetic resonance imaging help for the follow-up of synthetic hernia composite meshes fate? A pilot study

 Franconi F, Lefranc O, Radlovic A & Lemaire L

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Tailoring PEGylated nanoparticle surface modulates inflammatory response in vascular endothelial cells

Therani SF, Rabanel J-M, Legeay S, Cayon J, Riou J, Saulnier P, Marleau S, Roullin VG, Hildgen P & Bastiat G

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DDS for oral administration of antimicrobial peptides: Promising tools to treat infectious diseases

Deshayes C, Arafath MD, Apaire-Marchais V & Roger E

link to publisher        link to intranet   open acess

 

 

Cell penetrating peptide decorated magnetic porous silicon nanorods for glioblastoma therapy
and imaging

Chaix A, Griveau A, Defforge T, Grimal V, Le Borgne B, Gautier G and Eyer J

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Impact of anti-PDGRFa antibody surface functionnalization on LNC uptake by oligodendrocyte progenitor cells

Labrak Y, Heurtault B, Frisch B, Saulnier P, Lepeltier E, Miron VE, Muccioli GG & Des Rieux A

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Green Nanotechnology - An innovative pathway towards biocompatible and medically relevant gold nanoparticles

Thipe VG, Karikachery AR, Cakilkaya P, Farooq U,Genedy HH, Kaeokhamloed N, Phan DH, Rezwan R, Tezcan G, Roger E, Katti KV.

link to publisher        link to intranet

 

 

Interfacial tension of ethanol, water, and their mixtures in high pressure
carbon dioxide: Measurements and modeling

Fabien A, Lefebvre G, Calvignac  B, Legout P, Badens E &Crampon C

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Epoxiconazole profoundly alters rat brain and properties of neural stem cells

Hamdi H, Graiet I, Abid-Essefi S & Eyer J

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Modulating undruggable targets to overcome cancer therapy resistance

Passirani C, Vessières A, La Regina G, Link W & Silvestri R

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Stability of a high-concentrated aqueous solution of idarubicin stored in a polypropylene syringe for transarterial chemoembolization

Bourcier B, Lagarce F & Lebreton V

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Azacitidine Omega-3 Self-Assemblies: Synthesis, Characterization, and Potent Applications for Myelodysplastic Syndromes.

Baroud M, Lepeltier E, El-Makhour Y, Lautram N, Bejaud J, Thepot S & Duval O

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The evolution of nucleosidic analogues: self-assembly of prodrugs into nanoparticles for cancer drug delivery

Baroud M., Lepeltier E., Thepot S., El-Makhoure Y. & Duval O.

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Organic nanoparticle tracking during pharmacokinetic studies

Bonnet S., Elfatairi R., Franconi F., Roger E. & Legeay S.

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Local delivery and glioblastoma: Why not combining sustained release and targeting?

Gazaille C.*, Sicot M.*, Saulnier P., Eyer J & Bastiat G

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Microbiota and nanoparticles: Description and interactions

Ladaycia A, Passirani C & Lepeltier E

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Granting agencies

 

                                     

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