MINT new members

From Left to right:
ELWAER Imene obtained her Master’s degree in Cellular Biology and Physiology from the University of Monastir, Tunisia. During her final year, she completed a research internship at the Laboratory of Bioactive Natural Products and Biotechnology, where she investigated the cytotoxic and antioxidant activities of plant extracts, highlighting their potential as natural anticancer agents. She is currently pursuing her Ph.D. at the MiNT Laboratory under the supervision of Dr. Guillaume BASTIAT, focusing on the development of alkaloid-based nanocarriers for colorectal cancer treatment. Her academic and research background reflects a strong interest in nanomedicine, cancer biology, and natural bioactive compounds.
Tanguy LE LAY completed a Master’s degree in Drug-Design at the University of Caen, where he gained an interest in innovative drug delivery approaches. He began his career at UMR RIGHT in Besançon as a Research Engineer, working on a project involving the coating of silica nanoparticles with lipid nanocapsules. This experience allowed him to develop hands-on skills in nanoparticle formulation and lab work. He is now part of the MINT laboratory as a Research Engineer, working on lipid nanoparticles under the supervision of Pr Patrick Saulnier. His work is part of the SUCSEED project and mainly involves formulation, characterization and optimization, with a focus on developing delivery systems that can be applied in the agricultural field, particularly for seed coating.
Shreya Dey obtained BS-MS Dual Degree in Biological Sciences from IISER Kolkata,India. During her master’s degree she investigated the anti-migratory potential of fractions derived from the dichloromethane extract of Azadirachta indica stem bark. Under the supervision of Prof. Jayasri Das Sharma, she identified bioactive triterpenoid-rich fractions with strong anti-migratory and pro-apoptotic effects on cervical and lung carcinoma cells.She is currently a first-year Ph.D. student at the MiNT lab, working under the joint supervision of Prof. Nicolas Clere and Dr. Flavien Bessaguet. She is a recipient of the Eiffel Excellence Scholarship for the duration of her doctoral studies. She is working on the research project, STROMA which aims to decipher the role of the tumor stroma in non-small cell lung cancer (NSCLC) to better understand disease progression and improve therapeutic strategies.
Ana Lígia Blanco is a pharmaceutical scientist with a Bachelor’s and Master’s in Pharmaceutical Sciences from UNESP (Brazil). Master’s research focused on the development and physicochemical characterization of nanoemulsions for antifungal drug encapsulation as an innovative approach to treat systemic fungal infections. She is currently pursuing a PhD in Pharmaceutical Sciences at UNESP and at Angers University in the frame of a joint CAPES-COFECUB program, with research dedicated to nanotechnology-based drug delivery systems. Ongoing doctoral work conducted at MINT under the supervision of Dr Laurent Lemaire, focusing on the synthesis, surface modification, and biological evaluation of zinc oxide nanoparticles incorporated into nanoparticles for the treatment of resistant fungal infections
During her PhD at the PHYMA laboratory (MNHN), Dr. Clélia Guittonneau-Delestre studied the neurodevelopmental impact of Endocrine disrupting chemicals, alone or in combination, and their involvement from a regulatory viewpoint. She is currently starting a postdoctoral fellowship at the MINT laboratory with the financial support of Angers Loire Métropole, where she is working on the SITING project in collaboration with Dr. Franck Letournel and Dr. Julien Gouju. The main objective of this project is to demonstrate, in vitro, the passage of cyclosporine A and 4-IPP, via possible vectorization in lipid nanoparticles, through the nasal epithelium. This passage could enable the effective elimination of glioblastoma cells, including glioblastoma stem cells.

