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Micro et Nanomédecines translationnelles

Welcome to MINT's homepage

The MINT laboratory is funded by the University of Angers, as well as the French National Institute of Health and Medical Research (INSERM) and The French National Center for Scientific Research (CNRS). Located within the Hospital Facility, the MINT laboratory consists of 40 researchers and PhD students with expertise in diverse fields including; colloids and interfaces physical-chemistry; galenic; chemical engineering for pharmaceutical formulation; biological research; and imaging. All our research is focused on the design of nano- and micro-scaled vectors for the delivery of therapeutics (encompassing proteins, anti-cancer drugs, DNA, SiRNA, mRNA, etc.) and/or imaging probes.

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Recently published

 

 

Bimodal Poly(lactic-co-glycolic acid) Nanocarrier with Zinc Oxide and Iron Oxide for Fluorescence and Magnetic Resonance Imaging

Thúlio Wliandon Lemos Barbosa, Laurent Lemaire, Isabelle Verdu, Larissa Santos, Natália Galvão de Freitas, Mariana Picchi Salto and Leila Aparecida Chiavacci

 

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Heavy-Atom-Free Photosensitizer-Loaded Lipid Nanocapsules for Photodynamic Therapy

Oksana Kharchenko, Julien Gouju, Isabelle Verdu, Guillaume Bastiat, Piétrick Hudhomme, Catherine Passirani, Patrick Saulnier & Oksana Krupka

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Self-assemblies of cell-penetrating peptides and ferrocifens: design and biological evaluation of an innovative platform for lung cancer treatment
Léna Guyon, Abdallah Ladaycia, Agnese Bosio, Laurent Lemaire, Florence Franconia,
Bénédicte Lelièvre, Nolwenn Lautram, Pascal Pigeon, Gérard Jaouen, Catherine Passirani, Elise Lepeltier

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 One-Step Synthesis of Poly(2-alkyl-2-oxazoline)-Coated Gold Nanospheres: A Greener Approach for Biomedical Uses

Léa Daoud, Stéphane Hoang, Alexia Milin-Moguerou, Joël Eyer, Tony Breton, Véronique Montembault, Laurent Fontaine, Catherine Passirani, Patrick Saulnier, and Oksana Krupka

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Focus on the importance of the process parameters: temperature cycles and “shock” water addition during the phase inversion process for the formulation of lipid nanoparticles

Claire Gazaille, Sonia Pîgles, Krist´of Apr´o , Laura Ruesche , Aouatef Foudi , Adélie Mellinger  , Benjamin Siegler , Joel Eyer , Laurent Lemaire , Patrick Saulnier , Florence Franconi , Guillaume Bastiat

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Thymoquinone loaded lipid nanocapsule dispersion: two methods of preparation, characterization and in vitro evaluations for oral administration

Mouna Selmi, Amine Trabelsi, Nolwenn Lautram, David Dallerac, Guillaume Lefebvre, Leila Chekir Ghedira & Emilie Roger

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