Welcome on MINT homepage
The MINT laboratory is funded by the University of Angers, as well as the French National Institute of Health and Medical Research (INSERM) and The French National Center for Scientific Research (CNRS). Located within the Hospital Facility, the MINT laboratory consists of 40 researchers and PhD students with expertise in diverse fields including; colloids and interfaces physical-chemistry; galenic; chemical engineering for pharmaceutical formulation; biological research; and imaging. All our research is focused on the design of nano- and micro-scaled vectors for the delivery of therapeutics (encompassing proteins, anti-cancer drugs, DNA, SiRNA, etc.) and/or imaging probes.
News
Academic training
Master 2 NanoPharma Nanomedicines and Pharmaceutical R&D
European Master in nanomedecine & phamaceutical innovation
Recently published
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Topical delivery of curcumin-loaded transfersomes gel ameliorated rheumatoid arthritis by inhibiting NF-κβ pathway Sana E , Zeeshan M , Ain QU, Khan AU, Hussain I, Khan S, Lepeltier E & Ali H |
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New In Vitro Coculture Model for Evaluating Intestinal Absorption of Different Lipid Nanocapsules |
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Specificity of pharmacokinetic modeling of nanomedicines LebretonV, Legeay S, Saulnier P & Lagarce F |
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MDPI-Cancers |
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pH-Responsive Lipid Nanocapsules: A Promising Strategy for Improved Resistant Melanoma Cell Internalization Pautu V, Lepletier E, MellingerA, Riou J, Debuigne A, Jérôme C, Clère N & Passirani C |
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Effects of physical activity on cell-to-cell communication during type 2 diabetes: A focus on miRNA signaling Foudi N & Legeay S |
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Novel hybrid lipid nanocapsules loaded with a therapeutic monoclonal antibody – Bevacizumab – and Triamcinolone acetonide for combined therapy in neovascular ocular pathologies María Lina Formica, Samuel Legeay, Jérôme Bejaud, Guillermo Gabriel Montich, Gabriela Verónica Ullio Gamboa, Jean-Pierre Benoit, Santiago Daniel Palma |
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Vasculogenic mimicry, a complex and devious process favoring tumorigenesis – Interest in making it a therapeutic target Lucas Treps, Sébastien Faure, Nicolas Clere |
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Dietary sodium restriction sex specifically impairs endothelial function via mineralocorticoid receptor-dependent reduction in NO bioavailability in Balb/C mice Faulkner JL, Harwood D, Kennard S, Antonova G, Clere N and Belin de Chantemele EJ |
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p722 ferrocifen loaded lipid nanocapsules improve survival of murine xenografted-melanoma via a potentiation of apoptosis and an activation of CD8+ T lymphocytes Solene Topin-Ruiz, Adelie Mellinger, Elise Lepeltier, Clara Bourreau, Juliette Fouillet, Jeremie Riou, Gerard Jaouen, Ludovic Martin, Catherine Passirani, Nicolas Clere |
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Neuroprotective effects of Myricetin on Epoxiconazole-induced toxicity in Hiba Hamdi, Salwa Abid-Essefi, Joel Eyer |
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“All in One” Epoxy-Based Microfluidic Chips at Your Fingertips Simon Raffy, Etienne Palleau, Brice Calvignac, Guillaume Brotons, Guillaume Lefebvre, Nicolas Rolley, Sébastien Teychene, Bernard Viguier, Sara Castaño Cerezo, Gilles Truan, and Laurence Ressier |
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Microbiota and cancer: In vitro and in vivo models to evaluate nanomedicines Abdallah Ladaycia, Brigitta Loretz, Catherine Passirani, Claus-Michael Lehr, Elise Lepeltier |
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SPION and doxorubicin-loaded polymeric nanocarriers for glioblastoma theranostics Edurne Luque-Michel, Laurent Lemaire & Maria J. Blanco-Prieto |
Granting agencies
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