Welcome on MINT homepage

The MINT laboratory is funded by the University of Angers, as well as the French National Institute of Health and Medical Research (INSERM) and The French National Center for Scientific Research (CNRS). Located within the Hospital Facility, the MINT laboratory consists of 40 researchers and PhD students with expertise in diverse fields including; colloids and inferfaces physical-chemistry; galenic chemistry for pharmaceutical formulation; biological research; and imaging. All our research is focused on the design of nano- and micro-scaled vectors for the delivery of therapeutics (encompassing proteins, anti-cancer drugs, DNA, SiRNA, etc.) and/or imaging probes.

News

Design of new formulations for BCS lll drugs encapsulation

The December 1, 2020

Soutenance de Thèse de Mme Florence Dumas

Mr Kevin MATHA - nouveau docteur de l'Université d'Angers

The November 9, 2020

Formulation of innovative nanocarriers to treat visceral leishmaniasis

Mme Claire Gazaille - nouvelle docteure de l'Université d'Angers

The October 23, 2020

Lipid nanocapsules hydrogel combined with the NFL-TBS.40-63 peptide to prevent glioblastoma recurrences

Academic training

Master 2 NanoPharma Nanomedicines and Pharmaceutical R&D

European Master in nanomedecine & phamaceutical innovation

Recently published

		Targeted nanomedicine with anti-EGFR scFv for siRNA delivery into triple negative breast cancer cells Phuoc Vinh Nguyen, Katel Hervé-Aubert, Stéphanie David, Nolwenn Lautram, Catherine Passirani, Igor Chourpa, Nicolas Aubrey, Emilie Allard-Vannier
		Synthesis of PDMS‑b‑POEGMA Diblock Copolymers and TheirApplication for the Thermoresponsive Stabilization of Water-Supercritical Carbon Dioxide Emulsions Legout P, Lefebvre G, Bonnin M, Gimel JC, Benyahia L, Colombani O and Calvignac B. link to publisher
		Aqueous Two-Phase Systems: simple one-step process formulationand phase diagram for characterisation Dumas F, Roger E, Rodriguez J, Benyahia L & Benoit JP Link to publisher
		Lipid Nanoparticles Vectorized with NFL‑TBS.40‑63 Peptide Target Oligodendrocytes and Promote Neurotrophin‑3 Effects After Demyelination In Vitro Fressinaud C, Thomas O, Umerska AM & Saulnier P
		Novel hybrid lipid nanocapsules loaded with a therapeutic monoclonal antibody –Bevacizumab– and Triamcinolone acetonide for combined therapy in neovascular ocular pathologies Formica ML, Legeay S, Bejaud J, Montich GG, Ullio Gamboa GV, Benoit JP, Palma SD link to publisher
		Multidisciplinary Preclinical Investigations on Three Oxamniquine Analogues as Novel Drug Candidates for Schistosomiasis Buchter V, Ong Y C, Mouvet F, Ladaycia A, Lepeltier E, Rothlisberger U, Keiser J, and Gasser G link to publisher
		Endothelial-to-Mesenchymal Transition in Cancer Clère N, Renault S, Corre I full text
		Residual Solvents in Nanomedicine and Lipid-Based Drug Delivery Systems: a Case Study to Better Understand Processes Dikpati A, Mohammadi F, Greffard K, Quéant C, Arnaud P, Bastiat G, Rudkowska I & Bertrand N. Link to publisher

Granting agencies