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Micro et Nanomédecines translationnelles

Welcome on MINT homepage

The MINT laboratory is funded by the University of Angers, as well as the French National Institute of Health and Medical Research (INSERM) and The French National Center for Scientific Research (CNRS). Located within the Hospital Facility, the MINT laboratory consists of 40 researchers and PhD students with expertise in diverse fields including; colloids and inferfaces physical-chemistry; galenic chemistry for pharmaceutical formulation; biological research; and imaging. All our research is focused on the design of nano- and micro-scaled vectors for the delivery of therapeutics (encompassing proteins, anti-cancer drugs, DNA, SiRNA, etc.) and/or imaging probes.

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Academic training


Master 2 NanoPharma Nanomedicines and Pharmaceutical R&D


European Master in nanomedecine & phamaceutical innovation

Recently published



Targeted nanomedicine with anti-EGFR scFv for siRNA delivery into triple negative breast cancer cells

Phuoc Vinh Nguyen, Katel Hervé-Aubert, Stéphanie David, Nolwenn Lautram, Catherine Passirani, Igor Chourpa, Nicolas Aubrey,  Emilie Allard-Vannier



Synthesis of PDMS‑b‑POEGMA Diblock Copolymers and TheirApplication for the Thermoresponsive Stabilization of Water-Supercritical Carbon Dioxide Emulsions

Legout P, Lefebvre G, Bonnin M, Gimel JC, Benyahia L, Colombani O and Calvignac B.


Aqueous Two-Phase Systems: simple one-step process formulationand phase diagram for characterisation

Dumas F, Roger E, Rodriguez J, Benyahia L & Benoit JP


Lipid Nanoparticles Vectorized with NFL‑TBS.40‑63 Peptide Target Oligodendrocytes and Promote Neurotrophin‑3 Effects After Demyelination In Vitro

Fressinaud C, Thomas O, Umerska AM & Saulnier P


Novel hybrid lipid nanocapsules loaded with a therapeutic monoclonal antibody –Bevacizumab– and Triamcinolone acetonide for combined therapy in neovascular ocular pathologies

Formica ML, Legeay S, Bejaud J, Montich GG, Ullio Gamboa GV, Benoit JP, Palma SD


Multidisciplinary Preclinical Investigations on Three Oxamniquine Analogues as Novel Drug Candidates for Schistosomiasis

Buchter V,  Ong Y C, Mouvet F, Ladaycia A, Lepeltier E, Rothlisberger U, Keiser J, and Gasser G


Endothelial-to-Mesenchymal Transition in Cancer

Clère N, Renault S, Corre I

full text


Residual Solvents in Nanomedicine and Lipid-Based Drug Delivery Systems: a Case Study to Better Understand Processes
Dikpati A, Mohammadi F, Greffard K, Quéant C, Arnaud P, Bastiat G, Rudkowska I & Bertrand N.

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