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Micro et Nanomédecines Translationnelles

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    Welcome on MINT homepage

    The MINT laboratory is funded by the University of Angers, as well as the French National Institute of Health and Medical Research (INSERM) and The French National Center for Scientific Research (CNRS). Located within the Hospital Facility, the MINT laboratory consists of 40 researchers and PhD students with expertise in diverse fields including; colloids and inferfaces physio-chemistry; galenic chemistry for pharmaceutical formulation; biological research; and imaging. All our research is focused on the design of nano- and micro-scaled vectors for the delivery of therapeutics (encompassing proteins, anti-cancer drugs, DNA, SiRNA, etc.) and/or imaging probes.


    4 students for the NANOMED Erasmus Mundus Joint Master Degrees are joigning MINT

    students for the NANOMED Erasmus Mundus Joint Master Degrees are joigning MINT

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    Mme Janske NEL - nouvelle docteure de l'Université d'Angers

    1st March 2019

    Lipid nanocapsules as a theranostic tool : Soutenance de Thèse de Mme Janske NEL

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    Half a day in the labcoat of a MINT scientist

    undergraduate students from David d'Angers visit MINT Lab

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    Monsieur Brice CALVIGNAC, nouveau titulaire HDR

    13 December 2018

    Ingénierie des micro et nanotechnologies appliquées au développement de systèmes de délivrance de médicaments

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    Recently published


    Lipid nanocapsules as in vivo oxygen sensors using magnetic resonance imaging

    Nel J, Franconi F, Joudiou N, Saulnier P, Gallez B, Lemaire L


    UV-triggered photoinseertion of contast agent onto polymer surfaces for in vivo MRI-visible medical devices

    Schultz A, Lemaire L, Bethry A, Allegre L, Cardoso M, Bernex F, Franconi F, Goz-bac C, Taillades H, Garric X, Nottelet B


    Di-O-lauroyl-decitabine-lipid nanocapsules: toward extending decitabine activity

    Briot T., Roger E., Bou Haidar N., Bejaud J., Lautram N., Guillet C., Thépot S., Legeay S. & Lagarce F


    The immune suppressive microenvironment of human gliomas depends on the accumulation of bone marrow-derived macrophages in the center of the lesion

    Laura Pinton, Elena Masetto, Marina Vettore, Samantha Solito, Sara Magri, Marta D’Andolfi, Paola Del Bianco, Giovanna Lollo, Jean-Pierre Benoit, Hideho Okada, Aaron Diaz, Alessandro Della Puppa and Susanna Mandruzzato

    Albendazole-lipid nanocapsules: Optimization, characterization and chemoprophylactic efficacy in mice infected with Echinococcus granulosus.

    Ullio Gamboa GV, Pensel PE, Elissondo MC, Sanchez Bruni SF, Benoit JP, Palma SD, Allemandi DA.


    Controlled Anchoring of Iron-Oxide Nanoparticles on Polymeric Nanofibers: Easy Access to Core@Shell Organic-Inorganic Nanocomposites for Magneto-Scaffolds

    Awada Hussein, Samad Assala Al, Laurencin Danielle, Gilbert Ryan J, Dumail Xavier, jundi Ayman El, Bethry Audrey, Pomrenke Rebecca, Johnson Christopher, Lemaire Laurent, Franconi Florence, Félix Gautier, Larionova Joulia, Guari Yannick, Nottelet Benjamin


    Drug combination using an injectable nanomedicine hydrogel for glioblastoma treatment


    Bastiancich Chiara, Bozzato Elia, Luyten Urszula, Danhier Fabienne, Bastiat Guillaume, Préat Véronique


    Magnetite- and Iodine-Containing Nanoemulsion as a Dual Modal Contrast Agent for X-ray/Magnetic Resonance Imaging


    Wallyn justine, Anton Nicolas, Mertz Damien, Begin-Colin Sylvie, Pertron Francis, Serra A. Christophe, Franconi Florence, Lemaire Laurent, Chiper Manuela, Libouban Hélène, Messaddeq N, Anton Halina & Vandamme Thierry H.



    Lipid nanocapsules decorated and loaded with cannabidiol as targeted prolonged release carriers for glioma therapy: in vitro screening of critical parameters


    Aparicio-Blanco Juan, Sebastián Víctor, Benoît Jean-Pierre, Torres-Suárez Ana


    Preparation and evaluation of trityl-loaded lipid nanocapsules as oxygen sensors for electron paramagnetic resonance oximetry


    Nel Janske, Desmet Céline M, Driesschaert Benoit, Saulnier Patrick, Lemaire Laurent, Gallez Bernard


    Antimicrobial synergy of monolaurin lipid nanocapsules with adsorbed antimicrobial peptides against Staphylococcus aureus biofilms in vitro is absent in vivo


    Rozenbaum René T, Su Linzhu, Umerska Anita-Monika, Eveillard Matthieu, Håkansson Joakim, Mahlapuu Margit, Huang Fan Liu Jianfeng, Zhang Zhenkun, Shi Linqi, van der Mei Henny C, Bussche Henk J, Sharma Prashant K


    Reverse micelle-lipid nanocapsules: a novel strategy for drug delivery of the plectasin derivate AP138 antimicrobial peptide.


    Groo AC, Matougui N, Umerska A, Saulnier P.


    Melanoma tumour vasculature heterogeneity: from mice models to human.


    Pautu V, Mellinger A, Resnier P, Lepeltier E, Martin L, Boussemart L, Letournel F, Passirani C, Clere N.












    pilote de synthèse en milieu CO2 supercritiqueLaboratoire de culture cellulaireAnalyse thermiqueGranulométrieMesure tension interfacialeAnalyse LCMSMSPhoto_Unité_INSERM 1066 CNRS 6021Balance de Langmuir


    Institut de Biologie en Santé
    (3ème étage)
    Plateau des Capucins

    Coordonnées GPS

    de la gare,
    direction AVRILLÉ-ARDENNE,
    arrêt CAPUCINS

    Granting agencies